by James Lyons-Weiler, Popular Rationalism, ©2025
(Apr. 14, 2025) — A recent study out of Japan has sparked international attention and renewed discussion about the long-term biodistribution of COVID-19 mRNA vaccines. Reported by TrialSite News in early April 2025, the study led by Dr. Nakao Ota at Sapporo Teishinkai Hospital examined post-mortem brain tissues from patients who died of hemorrhagic stroke. In several cases, the research team reportedly detected SARS-CoV-2 spike protein still present in cerebral arteries—up to 17 months after the patients had received their final mRNA vaccination.
The study, published in Pathology – Research and Practice journal, does not claim a direct causal link between vaccination and the strokes, its findings—if confirmed—would represent the longest documented persistence of vaccine-induced spike protein in human tissue. The implications are both clinical and conceptual, raising foundational questions about how long vaccine products circulate, where they go, and how the body handles them over time.
This new report also aligns with a growing body of peer-reviewed research indicating that the spike protein, produced by mRNA vaccines, can persist far longer than initially expected. Among the most comprehensive syntheses of this literature to date is a review published in Pathology – Research and Practice (Scholkmann & May, 2023), which proposes a new, medically precise framework for understanding the short- and long-term effects of COVID-19 vaccination on human biology.
The Big Picture: Spike Protein Beyond the Injection Site
The core of the concern is biodistribution—where vaccine products go once injected and how long they remain biologically active. Originally, regulatory agencies and pharmaceutical companies described mRNA vaccines as remaining largely localized in muscle tissue, where cells would transiently express the SARS-CoV-2 spike protein, triggering a protective immune response. Clearance, it was said, would occur rapidly.
But that narrative has not held up entirely under scrutiny.
Multiple independent research teams have now shown that both spike protein and vaccine-derived mRNA can circulate well beyond the injection site and persist in the body for weeks, and in some cases, months. For example:
- Spike protein has been detected in blood plasma up to 28 days post-injection in hepatitis C patients who received mRNA vaccines (Yonker, ref$).
- Exosomes—tiny vesicles that ferry materials between cells—have been found to carry spike protein for up to 4 months after vaccination.
- Vaccine mRNA has been found in the plasma of vaccinated individuals up to 2 weeks post-injection, with potential to continue producing spike protein during that time.
- Lymph node biopsies showed abundant spike protein up to 60 days after the second dose.
Read the rest here.
You want justice? Give Anthony Fauci the COVID-19 “vaccine.”