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by Dr. Joseph Mercola, ©2023

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(May 1, 2023) — Before the COVID pandemic, Dr. Paul Marik became well-known for his development of a highly effective sepsis protocol using intravenous vitamin C, which resulted in a dramatic reduction in mortality rates. Then, in 2020, he cofounded the Front Line COVID-19 Critical Care Alliance (FLCCC) and subsequently published one of the most comprehensive and effective protocols for treating COVID-19.

Despite a stellar career up to that point, the sin of insisting on early treatment for COVID-19, and sharing that information with the public, resulted in him being vilified, discredited and ultimately forced to resign. I’m a veteran of this too, so much so that the first two times I attempted to interview Marik, he turned down the invitation, in part because of how I was being portrayed by the media.

“I was still digesting what was happening and I was unsure,” Marik says. “I didn’t realize how important you are in telling the truth and standing up for the truth. I was a little bit protective. We have subsequently met and, obviously, you’re one of my heroes because you stand up for the truth and you’ve known about the dishonesty, the deceit, the deception for much longer than I have.

I had swallowed the Kool-Aid. I was a tenured professor of medicine. I was the only one tenured in my department, in fact. I believed the medical literature, I believed the narrative. I believed what I taught, and you can understand how disturbing it is to one’s very core when you discover that what you’ve been teaching and promoting is based on lies, falsehood and deception.”

Indeed, it’s a hard pill to swallow for anyone, and I applaud Marik for having the courage and moral fortitude to follow the real evidence and not back down from the truth once it dawned on him. Some can’t handle it and simply stick their head in the sand and pretend they don’t know what they know.

COVID Revealed What the Medical System Is All About

As noted by Marik, COVID changed not only the world but medicine as well. Before COVID, intensive care specialists were relatively insulated against the evils of Big Pharma and they had therapeutic freedom. Their job was to save the patient using whatever means available, and they did so.

That changed when COVID came around. Suddenly, doctors were told to send patients home, without treatment, until or unless they were unable to breathe, at which point they were to put them on mechanical ventilation and follow a strict drug protocol. Together, these treatments proved deadly for most patients.

Marik was among those who refused to accept this and set out to develop treatment protocols, one for use in-hospital and another for early outpatient treatment.

“We had a really successful protocol for treating COVID in the hospital,” he says. “That’s how we really started the MATH+ protocol. We knew it was effective. My results were better than any of my colleagues’. But the hospital decided to basically outlaw what I was doing.

I was using safe FDA approved drugs which have been shown to be effective for COVID, and the hospital I worked at, the Sentara Healthcare system, publicly made a statement that the pharmacy would no longer dispense the medications I had used …

Basically, all I was left with was remdesivir. As we know, the use of remdesivir was halted for Ebola because it was shown to be a toxic drug that killed people. We know that Gilead and the National Institutes of Health (NIH) and [Dr. Anthony] Fauci committed scientific fraud in the conduction of the remdesivir study …

They committed out-and-out scientific fraud. We know, according to publicly available World Health Organization data, that remdesivir increases the risk of a patient developing renal failure 20-fold. We know it increases your risk of dying.

You can understand the situation that I was in. I was the director of the ICU. I had run the ICU for 15 years, and now I was told I can’t use safe and effective drugs to treat my patients. Rather, I must use a toxic drug for which the hospital gets an additional bonus.

That was a big awakening for me and it speaks to the depth, the breadth of corruption. Basically, the health care system is not patient-geared or health care-geared or geared to enlighten patients, improve their health, improve their lifespan, make them happy, improve their general health.

The system is designed to make money. Simple as that. Make money for Big Pharma. Make money for the hospitals and the system and therefore empower the NIH. That’s a brief overview of this journey that I’ve traveled. They have persecuted me professionally and personally. Their goal was to take me down and destroy my career.

They were somewhat successful in ending my clinical career, but I’m not going to give up. I will never give up because you have to fight for truth and honesty. I think now I have a much bigger role because I and you and many of us have revealed the deceit of the system, and we need to empower patients and health care providers to do what our Hippocratic duty is: To help patients. That’s what we’re here to do.”

The MATH+ Protocol

The initial MATH+ protocol the FLCCC developed in early 2020 got its name from:

  • Intravenous Methylprednisolone
  • Intravenous Ascorbic acid
  • Thiamine (B1)
  • Full dose low molecular weight Heparin
  • Plus optional treatments zinc, vitamin D and melatonin

Since then, the protocol has been revised several times as more data became available. Additional protocols have also been developed, including one for long-COVID and COVID jab injuries. You can find them all on the FLCCC’s website.

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Duty to the Patient Led to Sepsis Treatment Discovery

As explained by Marik, the MATH+ protocol grew out of his HAT protocol for sepsis, developed four years earlier.

“HAT stands for hydrocortisone, ascorbic acid and thiamine. How did this start? I’m a bedside clinician and as [Sir William] Osler said, ‘You learn medicine at the bedside.’ Why? Because that’s where the patient is … That’s where some of the most important discoveries are made, at the bedside. [In] January 2016, I had a patient who had overwhelming sepsis. I think she was in her 50s.

She had biliary sepsis. She arrived in the ICU. She became intubated. She was in renal failure. She was on multiple doses of vasopressors. As a doctor, I knew she was going to die … and when you’re at the bedside, you have a duty to the patient. The doctor always thinks, ‘What can I do to help this patient? Is there a rabbit I can pull out of the hat to help her?’

It just so happened I had read some work on vitamin C by Dr. [Alpha] Fowler and I was really impressed by his work. He had done a preliminary study looking at vitamin C in sepsis and I thought, ‘You know what? Why don’t I try it?’ It’s available in the hospital. It’s FDA approved. I called my pharmacist; we had vitamin C. I told them what I wanted to do. I explained to the family what we were going do. I decided to use vitamin C.

I was unclear about what dose to use. I looked at Dr. Fowler’s study and in his paper, he used two different doses, 50 milligrams per kilogram per day and 200 … We started off on 100 mg per kg per day, which came out to 1.5 grams every six hours …

I was always very impressed with hydrocortisone for sepsis. More recently, like a week ago, we now have a paper proving the lifesaving benefit of hydrocortisone in pneumonia. So, this wasn’t something I sucked out of the air.

Then I added thiamine because of its multiple beneficial effects. At first I thought it would help protect against oxalosis with vitamin C, but that wasn’t true. But thiamine actually has important effects in intermediary metabolism, mitochondrial function, energy, metabolism, and patients with sepsis are often both vitamin C deficient and thiamine deficient.

That was the initial rationale for this. I thought, ‘Well, what do we have to lose?’ I was convinced the next morning when I came to work, she would not be with us. I can tell you, I was completely dumbfounded and stunned. The next morning, she was sitting up in bed, she was off vasopressor agents. She got extubated. Her kidney function had improved, and she left the ICU three days later.

I was stunned. Our nurses were stunned. The residents were stunned. They’d never seen such a thing. This is a woman who we knew was going to die and she walked out of the hospital. When you see something like this, you say, ‘Wow, maybe that was just a fluke.’ But I did it again and again and again, and exactly the same thing happened.

We started this as a protocol in our ICU and this was endorsed by our nurses because they could see the dramatic effect. The nurses tell the truth. They’re the ones at the bedside … although the hospital tried to silence them.”


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Dr. Joseph Mercola is an osteopathic physician, as well as a best-selling author and expert in the field of natural health. Early in his medical career, he practiced conventional medicine but realized that the methods he learned in medical school weren’t working anymore. This led him to discover the wonderful world of holistic healing, a path that he continues to follow this day.

In 1997, Dr. Mercola founded Mercola.com to serve as a platform where he can share his analysis and other experiences to his audience. It is one of the earliest health websites that focuses on holistic medicine. It has since become one of the leading health websites.

Aside from running a website, Dr. Mercola is a prolific writer, having written 17 books, the latest being “The Truth About COVID-19: Exposing the Great Reset, Lockdowns, Vaccine Passports, and the New Normal.” Three of his books have been included in The New York Times Best Sellers list, specifically “Effortless Healing,” “The No-Grain Diet” and “The Great Bird Flu Hoax.”

Read more here.