by John Anthony, Sustainable Freedom Lab, ©2022
(Feb. 21, 2022) — A Feb 18 Malaysian Study of Ivermectin (I-Tech RCT) revealed the drug showed strong potential in fighting the SARS Cov2 virus.
More than 3X as many in the standard care (control) group required mechanical ventilation and more that 3X as many in the standard care group died. This despite the Ivermectin being administered to the sicker of two groups.
You would never recognize any of these impressive results from the report’s conclusion which reads:
“The study findings do not support the use of ivermectin for patients with COVID-19.”
You can read the full study here.
Let’s dig into the Malaysian study to see how the authors drew this conclusion that contradicts their own data.
Ivermectin administered later than recommended
Studies and doctor feedback indicate Ivermectin is effective when administered as an early treatment in 1 – 3 days. Yet participants in this study were enrolled in the program up to 7 days after symptoms appeared.
It is interesting this study references others in Columbia and Argentina as examples of no significant Ivermectin benefit. Both studies administered the drug later than recommended and still the Ivermectin performed better than the control groups.
Improbable primary endpoint
Every study has a main point to prove or disprove, called an endpoint or outcome. There are primary and secondary outcomes. Typically, disease progression would be a secondary outcome versus whether mechanical ventilation was required or if the patient died. The latter two are specific severe patient dependent outcomes.
But the authors reversed the importance of the outcomes. The primary outcome was disease progression. 52 (21.6%) of the Ivermectin group and 43 (17.3%) of the control patients progressed to severe disease.
This is the bulk of the authors’ argument for rejecting Ivermectin use. As you will see that argument holds less value on closer scrutiny.
More significant secondary outcomes
The study also shows 4 (1.7%) of the Ivermectin group versus 10 (4.0%) of the control group required ventilation. More importantly, 3 (1.2%) died in the treatment group versus 10 (4.0%) in the control group who died.
From Table 2 you can see 6% of the Ivermectin group died while 23% of the standard care group died.
Read the rest here.